The application of 0.8-kg and 0.6-kg ice packs led to a significantly greater decrease in the interface temperature compared with the 0.3-kg ice pack (0.8 kg vs. 0.3 kg). The lowest temperature during ice application was reached after 8-9 minutes of cooling.

Janwantanakul P. The effect of quantity of ice and size of contact area on ice pack/skin interface temperature. Physiotherapy. 2009 Jun;95(2):120-5.

CCT (cold compression therapy) decreased signs of pain, swelling, and lameness and increased stifle joint range of motion in dogs during the first 24 hours after TPLO.

Drygas KA, et al. Effect of cold compression therapy on postoperative pain, swelling, range of motion, and lameness after tibial plateau leveling osteotomy in dogs. J Am Vet Med Assoc. 2011 May 15;238(10):1284-91.

Use of cold compresses alone or with a bandage, or using microcurrent electrical therapy in combination with a bandage decreases soft tissue swelling over 72 hours more than a bandaging alone after extracapsular repair of CCLR.

Rexing J, et al. Effects of cold compression, bandaging, and microcurrent electrical therapy after cranial cruciate ligament repair in dogs. Vet Surg. 2010 Jan;39(1):54-8.